Notes from Monday BioMalPar mtg
New edition of Methods in Molecular Biology ... should post on PlasmoDB.
Peter Preiser: antibodies to two STEVOR proteins show stain RBC surface differently in different isolates. Haven't done colocalization or selections.
Tony Holder: Nice talk on new GPI-anchored MN protein ... PF8_008 (filtered based on proteomics data, SP+, hypothetical, expressed in merozoites and sporozoites only)
Freddy Frischknecht: Holding pathogen imaging workshop in Heidelberg ... of possible interest to Ina?
M Prudencio (Maria Mota's lab): nice talk on siRNA kinome screen for slatered spz invasion of hepatocytes. PKCzeta best bet, although probably nonspecific?
Rowena Martin (Kiaran Kirk's lab): Beautiful talk on PfCRT expressed in Xenopus oocytes. Shows Xport of labelled CQ in K76T mutant if external pH=6. Block with 76 K or S163R. Reverse with verapamil (IC50-30uM). Suggestive data indicates possible transport of polypeptide fragments of Hb with two aromatic AAs.
Jake Baum (WEHI): Beautiful talk on formin nucleation of actin (see recent publication)
1 comment:
Excellent!!! First real usage of the rooslab blog!
The microneme protein reported by Tony Holder is the one the presented on at mpm 2006? Gene ID should be corrected to PF08_0008.
The Rowena Martin talk sounds cool!
Look forward to more posts.
Cheers,
Omar
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